PBX2

PBX2
Dynodwyr
Cyfenwau	PBX2, G17, HOX12, PBX2MHC, PBX homeobox 2
Dynodwyr allanol	OMIM: 176311 HomoloGene: 48115 GeneCards: PBX2
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0001131, GO:0001151, GO:0001130, GO:0001204 DNA-binding transcription factor activity • sequence-specific DNA binding • DNA binding • transcription factor binding • chromatin binding • GO:0001948, GO:0016582 protein binding • RNA polymerase II transcription regulatory region sequence-specific DNA binding • GO:0001077, GO:0001212, GO:0001213, GO:0001211, GO:0001205 DNA-binding transcription activator activity, RNA polymerase II-specific • GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific Cydrannau o'r gell • cnewyllyn cell • transcription regulator complex Prosesau biolegol • proximal/distal pattern formation • GO:0009373 regulation of transcription, DNA-templated • embryonic limb morphogenesis • transcription, DNA-templated • transcription by RNA polymerase II • GO:0003257, GO:0010735, GO:1901228, GO:1900622, GO:1904488 positive regulation of transcription by RNA polymerase II Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	5089	n/a
Ensembl	ENSG00000224952 ENSG00000237344 ENSG00000236353 ENSG00000232005 ENSG00000225987 ENSG00000206315 ENSG00000204304	n/a
UniProt	P40425	n/a
RefSeq (mRNA)	NM_002586	n/a
RefSeq (protein)	NP_002577	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search	[1]	n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn PBX2 yw PBX2 a elwir hefyd yn PBX homeobox 2 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 6, band 6p21.32.^[2]

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn PBX2.

• G17
• HOX12
• PBX2MHC

• "Overexpression of PREP-1 in F9 teratocarcinoma cells leads to a functionally relevant increase of PBX-2 by preventing its degradation. ". J Biol Chem. 2003. PMID 12871956.
• "Fusion with E2A converts the Pbx1 homeodomain protein into a constitutive transcriptional activator in human leukemias carrying the t(1;19) translocation. ". Mol Cell Biol. 1994. PMID 7910944.
• "Variant of PBX2 gene in the 6p21.3 asthma susceptibility locus is associated with allergic rhinitis in Chinese subjects. ". Int Forum Allergy Rhinol. 2016. PMID 26852910.
• "Expression level of pre-B-cell leukemia transcription factor 2 (PBX2) as a prognostic marker for gingival squamous cell carcinoma. ". J Zhejiang Univ Sci B. 2012. PMID 22374608.
• "Expression level of Pre B cell leukemia homeobox 2 correlates with poor prognosis of gastric adenocarcinoma and esophageal squamous cell carcinoma.". Int J Oncol. 2010. PMID 20126986.