Propranolol
Propanolol (brand names Bedranol, Beta-prograne, Half Beta-prograne) belongs to a group of medicines called beta blockers. It is used to treat heart problems, help with some of the symptoms of anxiety and prevent migraines.[1]
For heart problems, propranolol can be taken to to:[1]
- treat high blood pressure
- treat conditions that cause an irregular heartbeat (arrhythmia), like atrial fibrillation
- help prevent future heart disease, heart attacks and stroke
- help prevent chest pain caused by angina
 | |
 | |
| Clinical data | |
|---|---|
| Pronunciation | /proʊˈprænəˌlɑːl/ |
| Trade names | Inderal, others |
| AHFS/Drugs.com | Monograph |
| License data |
|
| Pregnancycategory |
|
| Routes ofadministration | Oral, rectal, intravenous |
| ATC code |
|
| Pharmacokinetic data | |
| Bioavailability | 26% |
| Protein binding | 90% |
| Metabolism | Liver (extensive) CYP1A2, CYP2D6; minor: CYP2C19, CYP3A4 |
| Metabolites | N-desisopropylpropranolol, 4'-hydroxypropanolol |
| Elimination half-life | 4–5 hours |
| Excretion | Kidney (<1%) |
| Identifiers | |
| CAS Number | |
| PubChem CID | |
| IUPHAR/BPS | |
| DrugBank | |
| ChemSpider | |
| UNII | |
| KEGG | |
| ChEBI | |
| ChEMBL | |
| ECHA InfoCard | 100.007.618 |
| Chemical and physical data | |
| Chirality | Racemic mixture |
| (verify) | |
References
- ↑ 1.0 1.1 "Propranolol: medicine for heart problems, anxiety and migraine". nhs.uk. 2019-01-14. Retrieved 2024-06-04.