ERCC3

ERCC3
Нинди таксонда бар H. sapiens[d][1]
Кодлаучы ген ERCC3[d][1]
Молекуляр функция protein C-terminus binding[d][2][3], нуклеотид-связывающий[d][4], DNA helicase activity[d][5], protein kinase activity[d][6], гидролазная активность[d][4][4], ATP-dependent activity, acting on DNA[d][7][6], protein N-terminus binding[d][8], 3'-5' DNA helicase activity[d][9][10], АТФ-связанные[d][4][4], damaged DNA binding[d][11], ДНК-связывающий[d][7][4][4], transcription factor binding[d][12], связывание с белками плазмы[d][13][8][14][…], helicase activity[d][4][4], RNA polymerase II CTD heptapeptide repeat kinase activity[d][15], ATPase activity[d][2], DNA helicase activity[d][4][16], transcription factor binding[d][17][16], RNA polymerase II CTD heptapeptide repeat kinase activity[d][6][16], DNA translocase activity[d][18] һәм 3'-5' DNA helicase activity[d][7][2][16]
Күзәнәк компоненты transcription factor TFIIH core complex[d][5], төш[7][4][4], нуклеоплазма[d][4][4], transcription factor TFIIH holo complex[d][19][15][20], transcription factor TFIID complex[d][21], nucleotide-excision repair factor 3 complex[d][16], transcription factor TFIIH core complex[d][4][16], transcription factor TFIIH holo complex[d][22][6][14][…] һәм transcription preinitiation complex[d][16]
Биологик процесс response to hypoxia[d][4], termination of RNA polymerase I transcription[d][4], развитие эмбрионического органа[d][5], транскрипция, ДНК-зависимая[d][5], response to UV[d][23], 7-methylguanosine mRNA capping[d][4], nucleotide-excision repair, DNA incision[d][5][24][10], regulation of mitotic cell cycle phase transition[d][25], апоптоз[d][26], positive regulation of apoptotic process[d][27], фосфорилация белка[d][4], hair cell differentiation[d][28], response to oxidative stress[d][29], УФ-защита[d][4], cellular response to DNA damage stimulus[d][4], transcription initiation from RNA polymerase II promoter[d][5][5], global genome nucleotide-excision repair[d][4], protein localization[d][30], transcription elongation from RNA polymerase II promoter[d][4], ДНК-зависимая регуляция транскрипции[d][5], положительная регуляция транскрипции РНК полимеразой II промотор[d][31], DNA topological change[d][7], transcription initiation from RNA polymerase I promoter[d][4], transcription by RNA polymerase II[d][5][9][15], transcription-coupled nucleotide-excision repair[d][4][7], Эксцизионная репарация нуклеотидов[d][30][4], nucleotide-excision repair, preincision complex stabilization[d][4], репарация ДНК[d][11][4], вирусный процесс[d][4], nucleotide-excision repair, preincision complex assembly[d][4], nucleotide-excision repair, DNA incision, 5'-to lesion[d][4], nucleotide-excision repair, DNA duplex unwinding[d][10], regulation of mitotic recombination[d][18], nucleotide-excision repair, DNA duplex unwinding[d][10][18], promoter clearance from RNA polymerase II promoter[d][18], transcription open complex formation at RNA polymerase II promoter[d][18], transcription-coupled nucleotide-excision repair[d][5][9][18], response to UV[d][30][16], regulation of transposition, RNA-mediated[d][18], nucleotide-excision repair, DNA incision[d][4][2][31][…], hair cell differentiation[d][32][16], положительная регуляция транскрипции РНК полимеразой II промотор[d][24][18], развитие эмбрионического органа[d][4][16], phosphorylation of RNA polymerase II C-terminal domain[d][18], regulation of mitotic cell cycle phase transition[d][33][18], regulation of RNA polymerase II regulatory region sequence-specific DNA binding[d][18], nucleotide-excision repair, DNA duplex unwinding[d][4][2], nucleotide-excision repair, DNA incision, 3'-to lesion[d][4], transcription elongation from RNA polymerase I promoter[d][4], transcription by RNA polymerase II[d][4][7][6][…] һәм transcription initiation from RNA polymerase II promoter[d][4][4][16]
Изображение Gene Atlas

ERCC3 (ингл. ) — аксымы, шул ук исемдәге ген тарафыннан кодлана торган югары молекуляр органик матдә.[34][35]

Искәрмәләр

  1. ↑ 1,0 1,1 UniProt
  2. ↑ 2,0 2,1 2,2 2,3 2,4 Egly J., Oksenych V., Coin F. Distinct roles for the XPB/p52 and XPD/p44 subcomplexes of TFIIH in damaged DNA opening during nucleotide excision repair // Mol. Cell — Cell Press, Elsevier BV, 2007. — ISSN 1097-2765; 1097-4164 — doi:10.1016/J.MOLCEL.2007.03.009 — PMID:17466626
  3. ↑ Egly J. M., O Gileadi Distinct regions of MAT1 regulate cdk7 kinase and TFIIH transcription activities // J. Biol. Chem. / L. M. Gierasch — Baltimore [etc.]: American Society for Biochemistry and Molecular Biology, 2000. — ISSN 0021-9258; 1083-351X; 1067-8816 — doi:10.1074/JBC.M002578200 — PMID:10801852
  4. ↑ 4,00 4,01 4,02 4,03 4,04 4,05 4,06 4,07 4,08 4,09 4,10 4,11 4,12 4,13 4,14 4,15 4,16 4,17 4,18 4,19 4,20 4,21 4,22 4,23 4,24 4,25 4,26 4,27 4,28 4,29 4,30 4,31 4,32 4,33 4,34 4,35 4,36 4,37 4,38 GOA
  5. ↑ 5,00 5,01 5,02 5,03 5,04 5,05 5,06 5,07 5,08 5,09 GOA
  6. ↑ 6,0 6,1 6,2 6,3 6,4 E Kershnar, Wu S. Y., Chiang C. M. Immunoaffinity purification and functional characterization of human transcription factor IIH and RNA polymerase II from clonal cell lines that conditionally express epitope-tagged subunits of the multiprotein complexes // J. Biol. Chem. / L. M. Gierasch — Baltimore [etc.]: American Society for Biochemistry and Molecular Biology, 1998. — ISSN 0021-9258; 1083-351X; 1067-8816 — doi:10.1074/JBC.273.51.34444 — PMID:9852112
  7. ↑ 7,0 7,1 7,2 7,3 7,4 7,5 7,6 Egly J., Hoeijmakers J. H., T Seroz A 3' --> 5' XPB helicase defect in repair/transcription factor TFIIH of xeroderma pigmentosum group B affects both DNA repair and transcription // J. Biol. Chem. / L. M. Gierasch — Baltimore [etc.]: American Society for Biochemistry and Molecular Biology, 1996. — ISSN 0021-9258; 1083-351X; 1067-8816 — doi:10.1074/JBC.271.27.15898 — PMID:8663148
  8. ↑ 8,0 8,1 N Iyer, Reagan M. S., Wu K. J. et al. Interactions involving the human RNA polymerase II transcription/nucleotide excision repair complex TFIIH, the nucleotide excision repair protein XPG, and Cockayne syndrome group B (CSB) protein // Biochemistry / A. Schepartz — ACS, 1996. — ISSN 0006-2960; 1520-4995; 1943-295X — doi:10.1021/BI9524124 — PMID:8652557
  9. ↑ 9,0 9,1 9,2 Egly J., Hoeijmakers J. H., T Seroz A 3' --> 5' XPB helicase defect in repair/transcription factor TFIIH of xeroderma pigmentosum group B affects both DNA repair and transcription // J. Biol. Chem. / L. M. Gierasch — Baltimore [etc.]: American Society for Biochemistry and Molecular Biology, 1996. — ISSN 0021-9258; 1083-351X; 1067-8816 — doi:10.1074/JBC.271.27.15898 — PMID:8663148
  10. ↑ 10,0 10,1 10,2 10,3 Egly J., Oksenych V., Coin F. Distinct roles for the XPB/p52 and XPD/p44 subcomplexes of TFIIH in damaged DNA opening during nucleotide excision repair // Mol. Cell — Cell Press, Elsevier BV, 2007. — ISSN 1097-2765; 1097-4164 — doi:10.1016/J.MOLCEL.2007.03.009 — PMID:17466626
  11. ↑ 11,0 11,1 Hoeijmakers J. H. A presumed DNA helicase encoded by ERCC-3 is involved in the human repair disorders xeroderma pigmentosum and Cockayne's syndrome // Cell — Cell Press, Elsevier BV, 1990. — ISSN 0092-8674; 1097-4172 — doi:10.1016/0092-8674(90)90122-U — PMID:2167179
  12. ↑ Egly J., Hoeijmakers J. H. The XPB subunit of repair/transcription factor TFIIH directly interacts with SUG1, a subunit of the 26S proteasome and putative transcription factor // Nucleic Acids Res. — OUP, University of Oxford, 1997. — ISSN 0305-1048; 1362-4962; 1362-4954 — doi:10.1093/NAR/25.12.2274 — PMID:9173976
  13. ↑ Eggeling F. v., Baniahmad A. Detection and identification of transcription factors as interaction partners of alien in vivo // Cell Cycle / M. Blagosklonny — Landes Bioscience, Taylor & Francis, 2007. — ISSN 1538-4101; 1551-4005 — doi:10.4161/CC.6.8.4108 — PMID:17438371
  14. ↑ 14,0 14,1 Drapkin R. Human cyclin-dependent kinase-activating kinase exists in three distinct complexes // Proc. Natl. Acad. Sci. U.S.A. / M. R. Berenbaum — [Washington, etc.], USA: National Academy of Sciences [etc.], 1996. — ISSN 0027-8424; 1091-6490 — doi:10.1073/PNAS.93.13.6488 — PMID:8692842
  15. ↑ 15,0 15,1 15,2 E Kershnar, Wu S. Y., Chiang C. M. Immunoaffinity purification and functional characterization of human transcription factor IIH and RNA polymerase II from clonal cell lines that conditionally express epitope-tagged subunits of the multiprotein complexes // J. Biol. Chem. / L. M. Gierasch — Baltimore [etc.]: American Society for Biochemistry and Molecular Biology, 1998. — ISSN 0021-9258; 1083-351X; 1067-8816 — doi:10.1074/JBC.273.51.34444 — PMID:9852112
  16. ↑ 16,00 16,01 16,02 16,03 16,04 16,05 16,06 16,07 16,08 16,09 16,10 Livstone M. S., Thomas P. D., Lewis S. E. et al. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium // Brief. Bioinform. — OUP, 2011. — ISSN 1467-5463; 1477-4054 — doi:10.1093/BIB/BBR042 — PMID:21873635
  17. ↑ Egly J., Hoeijmakers J. H. The XPB subunit of repair/transcription factor TFIIH directly interacts with SUG1, a subunit of the 26S proteasome and putative transcription factor // Nucleic Acids Res. — OUP, University of Oxford, 1997. — ISSN 0305-1048; 1362-4962; 1362-4954 — doi:10.1093/NAR/25.12.2274 — PMID:9173976
  18. ↑ 18,00 18,01 18,02 18,03 18,04 18,05 18,06 18,07 18,08 18,09 18,10 Livstone M. S., Thomas P. D., Lewis S. E. et al. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium // Brief. Bioinform. — OUP, 2011. — ISSN 1467-5463; 1477-4054 — doi:10.1093/BIB/BBR042 — PMID:21873635
  19. ↑ Egly J., L. Schaeffer, V. Moncollin et al. p53 modulation of TFIIH-associated nucleotide excision repair activity, p53 modulation of TFIIH–associated nucleotide excision repair activity // Nature Genetics / M. Axton, T. Faial — NPG, 1995. — ISSN 1061-4036; 1546-1718 — doi:10.1038/NG0695-188 — PMID:7663514
  20. ↑ Drapkin R. Human cyclin-dependent kinase-activating kinase exists in three distinct complexes // Proc. Natl. Acad. Sci. U.S.A. / M. R. Berenbaum — [Washington, etc.], USA: National Academy of Sciences [etc.], 1996. — ISSN 0027-8424; 1091-6490 — doi:10.1073/PNAS.93.13.6488 — PMID:8692842
  21. ↑ Nogales E., Tjian R. Near-atomic resolution visualization of human transcription promoter opening // Nature / M. Skipper — NPG, Springer Science+Business Media, 2016. — ISSN 1476-4687; 0028-0836 — doi:10.1038/NATURE17970 — PMID:27193682
  22. ↑ Egly J., L. Schaeffer, V. Moncollin et al. p53 modulation of TFIIH-associated nucleotide excision repair activity, p53 modulation of TFIIH–associated nucleotide excision repair activity // Nature Genetics / M. Axton, T. Faial — NPG, 1995. — ISSN 1061-4036; 1546-1718 — doi:10.1038/NG0695-188 — PMID:7663514
  23. ↑ Khan S. G., Kraemer K. H. Influence of XPB helicase on recruitment and redistribution of nucleotide excision repair proteins at sites of UV-induced DNA damage // DNA Repair — Elsevier BV, 2007. — ISSN 1568-7864; 1568-7856 — doi:10.1016/J.DNAREP.2007.03.025 — PMID:17509950
  24. ↑ 24,0 24,1 Sancar A. Isolation and characterization of two human transcription factor IIH (TFIIH)-related complexes: ERCC2/CAK and TFIIH // Proc. Natl. Acad. Sci. U.S.A. / M. R. Berenbaum — [Washington, etc.], USA: National Academy of Sciences [etc.], 1996. — ISSN 0027-8424; 1091-6490 — doi:10.1073/PNAS.93.13.6482 — PMID:8692841
  25. ↑ Marini F., Giannattasio M., Plevani P. et al. DNA nucleotide excision repair-dependent signaling to checkpoint activation // Proc. Natl. Acad. Sci. U.S.A. / M. R. Berenbaum — [Washington, etc.], USA: National Academy of Sciences [etc.], 2006. — ISSN 0027-8424; 1091-6490 — doi:10.1073/PNAS.0605446103 — PMID:17088560
  26. ↑ Hoeijmakers J. H. The XPB and XPD DNA helicases are components of the p53-mediated apoptosis pathway // Genes Dev. — Cold Spring Harbor Laboratory Press, 1996. — ISSN 0890-9369; 1549-5477 — doi:10.1101/GAD.10.10.1219 — PMID:8675009
  27. ↑ Hu G., Liu L., Zhang J. et al. The role of XPB in cell apoptosis and viability and its relationship with p53, p21(waf1/cip1) and c-myc in hepatoma cells // Digestive and Liver Disease — Elsevier BV, 2006. — ISSN 1590-8658; 1878-3562 — doi:10.1016/J.DLD.2006.06.009 — PMID:16914395
  28. ↑ Egly J. Trichothiodystrophy, a transcription syndrome // Trends in Genetics — Elsevier BV, 2001. — ISSN 0168-9525; 1362-4555 — doi:10.1016/S0168-9525(01)02280-6 — PMID:11335038
  29. ↑ Kirsch-Volders M., Roelants M. Genetic susceptibility of newborn daughters to oxidative stress // Toxicol. Lett. — Elsevier BV, 2007. — ISSN 0378-4274; 1879-3169 — doi:10.1016/J.TOXLET.2007.05.014 — PMID:17614221
  30. ↑ 30,0 30,1 30,2 Khan S. G., Kraemer K. H. Influence of XPB helicase on recruitment and redistribution of nucleotide excision repair proteins at sites of UV-induced DNA damage // DNA Repair — Elsevier BV, 2007. — ISSN 1568-7864; 1568-7856 — doi:10.1016/J.DNAREP.2007.03.025 — PMID:17509950
  31. ↑ 31,0 31,1 Sancar A. Isolation and characterization of two human transcription factor IIH (TFIIH)-related complexes: ERCC2/CAK and TFIIH // Proc. Natl. Acad. Sci. U.S.A. / M. R. Berenbaum — [Washington, etc.], USA: National Academy of Sciences [etc.], 1996. — ISSN 0027-8424; 1091-6490 — doi:10.1073/PNAS.93.13.6482 — PMID:8692841
  32. ↑ Egly J. Trichothiodystrophy, a transcription syndrome // Trends in Genetics — Elsevier BV, 2001. — ISSN 0168-9525; 1362-4555 — doi:10.1016/S0168-9525(01)02280-6 — PMID:11335038
  33. ↑ Marini F., Giannattasio M., Plevani P. et al. DNA nucleotide excision repair-dependent signaling to checkpoint activation // Proc. Natl. Acad. Sci. U.S.A. / M. R. Berenbaum — [Washington, etc.], USA: National Academy of Sciences [etc.], 2006. — ISSN 0027-8424; 1091-6490 — doi:10.1073/PNAS.0605446103 — PMID:17088560
  34. ↑ HUGO Gene Nomenclature Commitee, HGNC:29223 (ингл.). әлеге чыганактан 2015-10-25 архивланды. 18 сентябрь, 2017 тикшерелгән.
  35. ↑ UniProt, Q9ULJ7 (ингл.). 18 сентябрь, 2017 тикшерелгән.

Чыганаклар

  • Степанов В.М. (2005). Молекулярная биология. Структура и функция белков. Москва: Наука. ISBN 5-211-04971-3.(рус.)
  • Bruce Alberts, Alexander Johnson, Julian Lewis, Martin Raff, Keith Roberts, Peter Walter (2002). Molecular Biology of the Cell (вид. 4th). Garland. ISBN 0815332181.(ингл.)


Миоглобин молекуласы
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